Danish trial icd

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August undefined, 2024

WebOct 31, 2024 · The recent publication of the Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) trial (Køber et al., 2016), which showed the absence of a reduction of total mortality in the patients randomized to ICD, is forcing us to rethink the selection criteria for ICD therapy in DCM ... WebMay 19, 2024 · In 2016, the DANISH trial, largest trial addressing this topic, was published including 1116 symptomatic NICM patients followed up for a mean period of 67.6 months. The DANISH trial showed no significant difference between the ICD group and optimal medical therapy (OMT) group as regards the primary outcome of all-cause mortality.

Defibrillator Implantation in Patients with Nonischemic Systolic Heart

WebOct 12, 2007 · Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH) The safety and scientific validity of this study is the responsibility of the study sponsor and … WebMar 7, 2024 · Treatment with ICD was associated with a 23% risk reduction for all-cause mortality, and a 57% risk reduction for SCD. 48 These findings, together with the findings from the DANISH trial (great advantage in patients <70 years or those without diabetes), highlight the need for improved patient selection when referring patients with NICM for an ... diamond clear balloons

Danish Study to Assess the Efficacy of ICDs in Patients …

WebJun 18, 2024 · To the Editor: Elming et al 1 report that the efficacy of primary prevention implantable cardioverter-defibrillator (ICD) therapy is diminished among older participants of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality), which randomized patients with … WebDec 3, 2024 · The 2016 Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) randomized 1116 patients … WebAug 28, 2016 · The DANISH trial failed to show that routine implantable cardioverter-defibrillator (ICD) implantation improved survival among patients with nonischemic … diamond clear car wax

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Primary Prevention Implantable Cardioverter Defibrillators in …

WebConclusions Although our updated meta-analysis demonstrates a survival benefit of ICD therapy, the effect is substantively weakened by the inclusion of the DANISH trial—which is both the largest and most recent of the … WebThe detailed design of the DANISH trial was reported previ-ously.7 In brief, DANISH was a randomized controlled trial addressing ICD implantation in patients with nonischemic systolic heart failure.3 In total, 1116 patients with docu-mented nonischemic systolic heart failure with left ventricu- diamond clear chartWebNov 25, 2024 · Recent findings: Recent studies including the Danish study to assess the efficacy of ICDs in patients with non-ischemic systolic heart failure on mortality … circuit breaker lightning

"WebDec 14, 2024 · For the DANISH trial, investigators at five ICD-implanting centers in Denmark enrolled 1,116 patients with nonischemic systolic heart failure, an LVEF of 35% or … " - Danish trial icd

Danish trial icd

Frontiers Implantable Cardioverter-Defibrillator in Dilated ...

WebMethods In this post hoc analysis of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients with Nonischemic Systolic Heart Failure on Mortality), patients with nonischemic systolic heart failure randomized to ICD or control underwent cardiovascular magnetic resonance. RV systolic dysfunction was defined as RVEF ≤45%. WebAug 28, 2016 · The Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH) delivers two important lessons: the specific one deals with ICD use in patients with heart …

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WebConclusions Although our updated meta-analysis demonstrates a survival benefit of ICD therapy, the effect is substantively weakened by the inclusion of the DANISH … WebApr 18, 2024 · The DANISH study therefore seems to already have had a high impact on clinical decision making for primary prevention ICD in the medical community. Only 40% of centres reported to implant primary prevention ICD in >75% of all patients with non-ischaemic disease fulfilling current recommendations.

WebOct 12, 2007 · Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ClinicalTrials.gov Identifier: NCT00542945 WebJan 18, 2024 · While ICD therapy is indicated for patients with both ICM and NICM, support for the ICD in primary prevention of sudden cardiac death is much stronger for patients with the ischemic disease. Prior pooled analyses of randomized trials showed benefits of an ICD in the setting of nonischemic disease, but the most recent study (DANISH) did not ...

WebSecond, medical therapy in both groups in the DANISH trial was superior to that used in clinical practice. 4,6 Third, the DANISH trial is the only trial to date to require an … WebTrial Oversight. The Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality …

WebAug 13, 2024 · In contrast, the more recent randomized Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) trial investigated the role of primary prevention ICDs exclusively in non-ischemic cardiomyopathy; it demonstrated a significant reduction in sudden cardiac death in …

WebFeb 1, 2024 · Similarly to the RR, the risk difference of SCD for ICD patients with respect to controls showed a progressive increase, from negative values of −9.7% and −18.0% in the MADIT and MUSTT trials to −3.9% in the DANISH trial (R 2 = 0.53, p = 0.06), which indicated a progressive decrease of the efficacy of ICD therapy. circuit breaker list diamond clear dryWebAug 28, 2016 · In the Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality (DANISH) of about 1100 symptomatic patients with an LVEF < 35 on optimal meds... diamond clear by paint prosWebSep 22, 2024 · This was a prespecified subgroup analysis of the 1,116 patients from the DANISH (Danish Study to Assess the Efficacy of ICDs in Patients with Non … circuit breaker listing templateWebMar 14, 2024 · In this post hoc analysis of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients with Nonischemic Systolic Heart Failure on Mortality), patients with nonischemic systolic heart … circuit breaker list templateWebSep 29, 2016 · In this trial, prophylactic ICD implantation in patients with symptomatic systolic heart failure not caused by coronary artery disease was not associated with a … circuit breaker load testerWebAug 29, 2024 · In the DANISH trial, patients in the medical therapy and ICD arms were also stratified according to CRT implantation status; survival was not statistically different in the ICD group as compared to medical therapy in patients who had CRT device implanted (HR 0.91, 95% CI 0.64–1.29, P=0.59) or those who did not (HR 0.83, 95% CI 0.58–1.19, … diamond clear data sheet