Web1 Apr 2024 · The rods and rings patterns as well as nuclear mitotic apparatus (NuMA)-like antibodies were not positive at 1:600 titer indicating low concentration of these … Web7 Jan 2024 · Cytoplasmic ANA patterns of AILD and non-AILD groups were compared. Further subgroup analysis of patients with AILD who had reticular or speckled …
Approach to the Patient With a Positive Antinuclear Antibody …
Web1 Oct 2024 · Although it has since been determined that the major component of these rod and ring structures is the enzyme inosine monophosphate dehydrogenase (IMPDH, discussed further in Section 2.1) [27,28,32], the autoantigen responsible for this staining pattern was not known in the beginning, so the pattern was named the “rods and rings” … Web1 Jan 2014 · Rods and rings (RR) are distinct cytoplasmic structures known to be composed of at least two enzymes critical for pyrimidine and purine synthesis. Due to the considerable size of these rods (3–10 μm in length) and rings (2–5 μm in diameter), RR are likely comprised of other unidentified proteins that may be related to nucleotide metabolism. sythesia custom midi
The significance of cytoplasmic antinuclear antibody patterns in
Web1 Apr 2024 · ANA assays represent about 30% of overall autoantibody determinations in a basic laboratory set up [2]. Some ANA patterns have been studied extensively and were … Web7 Jan 2024 · Cytoplasmic ANA patterns of AILD and non-AILD groups were compared. Further subgroup analysis of patients with AILD who had reticular or speckled … Web23 Nov 2024 · There is no unanimity on classifying DFS, rods and rings and polar/Golgi-like as a competent pattern and on reporting cytoplasmic patterns as ANA IIF positive. This survey confirms that the major nuclear and cytoplasmic ANA IIF patterns are considered clinically important. sythesis short review